Ignite part 1. When it’s not what you think: PID or SID?

Explore the complex interplay between primary and secondary immunodeficiencies (PID and SID) and their association with cancer and autoimmune diseases. The following two videos highlight the challenges in distinguishing between PID and SID, and the implications for patient management and screening.

Accurate diagnosis and advanced molecular diagnostics in differentiating and managing PID and SID: the need for interdisciplinary approaches to improve patient outcomes

This session delves into the diagnostic challenges of distinguishing primary immunodeficiency (PID) from secondary immunodeficiency (SID), particularly in the context of haematological malignancies, additionally suggesting the need for improved screening protocols and interdisciplinary approaches to enhance patient care.

Interdisciplinary approaches and early diagnosis in managing PID and SID in haematologic cancer patients: implications for patient care

Focusing on the genetic and clinical intersections between PID and SID, especially regarding cancer predisposition, the presentation goes on to introduce the PID Life Index as a tool for improving care. Also highlighted is the need for a multiparameter approach to early PID screening and the development of preventive strategies for patients and their families.